Abstract Pentamidine and melarsoprol are primary drugs used to treat the lethal human sleeping sickness caused by the parasite Trypanosoma brucei.Cross-resistance to these two drugs has recently been linked to aquaglyceroporin 2 of the Pill Boxes trypanosome (TbAQP2).TbAQP2 is the first member of the aquaporin family described as capable of drug tr
Weevils represent one of the most speciose and economically important animal clades, but remain poorly studied across much of the Oriental Region.Here, an integrative revision of the Oriental, flightless genus Aphanerostethus Voss, 1957 (Curculionidae: Molytinae) based on X-ray microtomography, multi-gene DNA barcoding (CO1, Cytb, 16S), and traditi
Goal of research.Research of new documents from the archives of the Nizhyn Greek Bro therhood, related to the stay of the Greek educator, professor of the Greek Academy in Jassy, Dimitrios Gobdelas in Moscow in 1812.To publish the texts of the documents with a translation into modern Ukrainian, to find out the specifics of the activity of Dimitrios
Abstract A characterization technique, including a mathematical model involving extensive computational resources, is introduced to study the behavior of an electro-optical space switch based on semiconductor optical amplifier (SOA).The model Mists encompasses the precise emulation of device nonlinearities and its transient performance, allowing th
Autoimmune diseases (ADs) represent a heterogeneous group of disorders that affect specific target organs or multiple organ systems.These conditions share common immunopathogenic mechanisms (i.e., the autoimmune tautology), which explain the clinical similarities they have among them as well as their familial clustering (i.e., coaggregation).As par